منابع مشابه
BriefDefinitive Report AURICULAR CHONDRITIS IN RATS
Relapsing polychondritis is an inflammatory disease of connective tissue characterized by the destruction of hyaline and elastic cartilages . Although the etiology of this disease is unknown, the demonstration of anti-cartilage antibodies in the sera of patients with this disorder suggests an autoimmune mechanism (1, 2) . Recently, Foidart et al . (3) have reported an association between relaps...
متن کاملRecurrent auricular chondritis and cartilage repair.
W e present a case of recurrent auricular chondritis, which developed after two injections of a luteinising hormone-releasing hormone (LH-RH) analogue buserelin combined with oral treatment of a pure antiandrogen bicalutamide (Casodex). The patient was treated successfully with a continuous moderate dose of corticosteroids together with azathioprine and methotrexate. Complete repair of the defo...
متن کاملAuricular chondritis in rats. An experimental model of relapsing polychondritis induced with type II collagen
Outbred Wistar rats immunized with native type II collagen developed ear lesions resembling those of human relapsing chondritis. As in human disease, these lesions were characterized by intense chondritis, positive immunofluorescence reactions to IgG and C3, and circulating IgG reactive with native type II collagen. Furthermore, electron-dense deposits were seen near the surface of chondrocytes...
متن کاملAuricular chondritis and diffuse proliferative glomerulonephritis in primary Sjögren's syndrome.
Bilateral auricular inflammation with histological changes of relapsing polychondritis was observed in a female patient with primary Sjögren's syndrome. This was accompanied by rapidly progressive renal insufficiency due to diffuse proliferative glomerulonephritis. To our knowledge this is the first well documented case of primary Sjögren's syndrome associated with chondritis and glomerulonephr...
متن کاملAuricular chondritis associated with systemic joint and cartilage inflammation in a cat.
An adult, Japanese domestic cat presented with bilateral swelling, distortion, and erythema of ears and deformation of the limbs. Biopsy of the pinnae confirmed auricular chondritis. These lesions and the cat's general condition subsequently deteriorated, and the cat died. At necropsy, chondral changes were present in the pinnae, costae, larynx, trachea, and limbs. Histopathologically, these ch...
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ژورنال
عنوان ژورنال: Laboratory Animals
سال: 1990
ISSN: 0023-6772,1758-1117
DOI: 10.1258/002367790780866092